Benzalkonium Chloride Hand Sanitizer Antibacterial Effect
The antimicrobial effects of quaternary ammonium compounds qacs such as benzalkonium chloride were first described in the 1900s.
Benzalkonium chloride hand sanitizer antibacterial effect. It s become such a sought after product that pharmacies and supermarkets have started limiting the number that people can. What is benzalkonium chloride used for. Benzalkonium chloride is primarily used as a preservative and antimicrobial agent and secondarily used as a surfactant. 1 under laboratory conditions benzalkonium chloride demonstrates decent activity against some bacteria fungi and enveloped viruses.
Benzalkonium chloride bak otherwise known as alkyl dimethyl benzyl ammonium chloride is a toxic chemical used in cosmetics it is a antimicrobial agent deodorant surfactant and a preservative. It works by killing microorganisms and inhibiting their future growth and for this reason frequently appears as an ingredient in antibacterial hand wipes antiseptic creams and anti itch ointments. Aden andrus academic medical research technical 3. However a potential negative effect is that the active ingredients will irritate the skin because of their continued presence on the skin surface.
As a cationic detergent in the family of quaternary ammonium compounds benzalkonium chloride bzk shows strong antiseptic activity against both gram positive and negative bacteria. Benzalkonium chloride has repeatedly demonstrated its toxic characteristics in laboratory experimental and clinical studies. Researchers at the los alamitos unified school district in california conducted a five week study in 2001 and found that students who used hand sanitizer containing benzalkonium chloride at scheduled times each day were 33 percent less likely to be absent due to illness. Bondurant md a collette m.
Demonstrating the persistent antibacterial efficacy of a hand sanitizer containing benzalkonium chloride on human skin at 1 2 and 4 hours after application author links open overlay panel sidney w. Usually alcohol based hand sanitisers contain between 60 95 alcohol. Manufacturers add other ingredients for various reasons. Since the outbreak of covid 19 sales of hand sanitizers have soared.
Ingredients such as glycerol. Hand hygiene says it s difficult to assess the effectiveness of alcohol free hand sanitizers because no standardized ingredient exists 1 2. Recently alcohol free hand sanitizers with triclosan or benzalkonium chloride have been gaining ground due to concerns that ethanol is dries out the skin is too toxic and there are frequent cases of intentional ingestion 10 14 17. These include additional agents which are active against viruses or bacteria such as chlorhexidine or benzalkonium chloride.
Duley bs b john w. This study was performed to evaluate the effectiveness of a new commercially available hand sanitizer using 0 12 benzalkonium chloride bzk as the active ingredient in reducing transient skin contamination with staphylococcus aureus in health care workers hcws as compared with the effectiveness of a 70 ethanol based hand sanitizer.
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